CoQ10 IV
About
About CoQ10 IV
Intravenous coenzyme Q10 (ubiquinol/ubiquinone) bypasses the limited oral bioavailability of CoQ10 to achieve therapeutic plasma and tissue concentrations for mitochondrial support, cardioprotection, and neurological applications. IV CoQ10 has been used in clinical settings for heart failure, Parkinson's disease, and mitochondrial disorders. It is a key component of comprehensive longevity IV drip protocols.
Science
Mechanism of Action
Functions as an electron carrier in the mitochondrial electron transport chain at complexes I-III, directly supporting ATP synthesis; acts as a lipid-soluble antioxidant protecting mitochondrial membranes from oxidative damage; regenerates vitamins C and E.
Dosing
Typical Protocol
100–300 mg IV infusion over 2–4 hours, 1–2x per week; often part of comprehensive IV nutrition protocols.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound is legal to prescribe and dispense through a licensed 503A or 503B compounding pharmacy with a valid prescription. It is not FDA-approved as a finished drug product, but compounding is explicitly permitted under federal law. Quality and sterility standards vary by pharmacy — look for PCAB-accredited compounders.
Evidence
Evidence Tier
Evidence primarily from animal studies, cell cultures, or small pilot human trials. Results are promising but have not yet been confirmed in large-scale human RCTs. Effects in humans may differ from animal models.
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