Epitalon
About
About Epitalon
Epitalon (epithalamin) is a synthetic tetrapeptide developed by the St. Petersburg Institute of Bioregulation and Gerontology, with decades of Russian research suggesting telomere lengthening, pineal gland regulation, and lifespan extension in animal models. It stimulates telomerase activity — a rare property among known compounds. Human data is limited but promising for longevity applications. It is widely used in anti-aging clinics.
Science
Mechanism of Action
Activates telomerase enzyme in somatic cells, elongating telomeres and potentially reversing a key molecular marker of cellular aging; also regulates melatonin production via the pineal gland to restore circadian rhythm.
Dosing
Typical Protocol
5–10 mg subcutaneous or IV injection once daily for 10–20 day cycles, 1–2x yearly.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound occupies a regulatory grey area in 2026. It is neither explicitly FDA-approved nor clearly illegal for personal use, but it lacks formal clinical approval and may not be legally sold for human use in all contexts. Proceed with caution: source quality is variable, and regulatory status can change. Always consult a physician.
Evidence
Evidence Tier
Evidence primarily from animal studies, cell cultures, or small pilot human trials. Results are promising but have not yet been confirmed in large-scale human RCTs. Effects in humans may differ from animal models.
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