Cortagen
About
About Cortagen
Cortagen is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Pro) targeting brain cortex function, developed by the St. Petersburg Institute of Bioregulation. Russian research suggests it improves cognitive function, stress resilience, and neurological recovery in aging populations. It is part of the same peptide bioregulator family as epitalon, vilon, and pinealon, designed to restore tissue-specific gene expression patterns.
Science
Mechanism of Action
Proposed to act as a cortical bioregulator that normalizes gene expression in cortical neurons, enhancing protein synthesis, neurotrophic factor production, and synaptic plasticity through chromatin-level regulatory mechanisms.
Dosing
Typical Protocol
5–10 mg subcutaneous injection daily for 10-day courses; typically cycled seasonally.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound occupies a regulatory grey area in 2026. It is neither explicitly FDA-approved nor clearly illegal for personal use, but it lacks formal clinical approval and may not be legally sold for human use in all contexts. Proceed with caution: source quality is variable, and regulatory status can change. Always consult a physician.
Evidence
Evidence Tier
Evidence primarily from animal studies, cell cultures, or small pilot human trials. Results are promising but have not yet been confirmed in large-scale human RCTs. Effects in humans may differ from animal models.
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