Pinealon
About
About Pinealon
Pinealon is a synthetic tripeptide (Ala-Glu-Asp-Gly) developed by the St. Petersburg Institute of Bioregulation and Gerontology, purported to regulate pineal gland function, improve sleep quality, and provide neuroprotective effects in aging. Russian clinical research suggests benefits for cognitive function, retinal health, and circadian rhythm normalization in older adults. It is used in anti-aging protocols alongside epitalon and other bioregulator peptides.
Science
Mechanism of Action
Proposed to act as a pineal gland bioregulator, normalizing melatonin synthesis and secretion while exerting direct neuroprotective effects on retinal cells and cortical neurons through gene expression modulation and antioxidant activity.
Dosing
Typical Protocol
5–10 mg subcutaneous injection daily for 10–20 day cycles; typically administered 1–2 times per year.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound occupies a regulatory grey area in 2026. It is neither explicitly FDA-approved nor clearly illegal for personal use, but it lacks formal clinical approval and may not be legally sold for human use in all contexts. Proceed with caution: source quality is variable, and regulatory status can change. Always consult a physician.
Evidence
Evidence Tier
Evidence primarily from animal studies, cell cultures, or small pilot human trials. Results are promising but have not yet been confirmed in large-scale human RCTs. Effects in humans may differ from animal models.
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