Selank
About
About Selank
Selank is a synthetic analog of the endogenous tetrapeptide tuftsin, developed in Russia for anxiety and cognitive enhancement. It provides anxiolytic effects comparable to benzodiazepines without the sedation, tolerance, or dependence risks. It also shows immunomodulatory and nootropic properties. Like semax, it is approved in Russia but used as a research compound in the US.
Science
Mechanism of Action
Modulates GABAergic neurotransmission and serotonin metabolism to produce anxiolysis; upregulates expression of BDNF and IL-6 in hippocampal tissue, contributing to its cognitive-enhancing and neuroprotective properties.
Dosing
Typical Protocol
250–500 mcg intranasal spray 1–2x daily; typically cycled 2–4 weeks on with breaks.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound occupies a regulatory grey area in 2026. It is neither explicitly FDA-approved nor clearly illegal for personal use, but it lacks formal clinical approval and may not be legally sold for human use in all contexts. Proceed with caution: source quality is variable, and regulatory status can change. Always consult a physician.
Evidence
Evidence Tier
Evidence primarily from animal studies, cell cultures, or small pilot human trials. Results are promising but have not yet been confirmed in large-scale human RCTs. Effects in humans may differ from animal models.
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This page evaluates compliance signals, not clinical outcomes. Consult a licensed physician before starting any therapy, medication, or treatment. Vial does not provide medical advice.