Taurine
About
About Taurine
Taurine is a conditionally essential sulfur amino acid abundant in heart, brain, and skeletal muscle, shown to extend median lifespan in mice by 12% and worms and flies proportionally in a 2023 Science paper by Singh et al. Taurine levels decline dramatically with age in humans and mice. Clinical research links higher taurine levels to reduced metabolic disease, better cardiovascular markers, and improved physical performance. It is widely available as a supplement.
Science
Mechanism of Action
Regulates intracellular calcium signaling, mitochondrial membrane potential, and osmotic homeostasis; suppresses cellular senescence and inflammation through NF-κB inhibition; serves as a neuromodulator at GABA-A and glycine receptors; supports bile acid conjugation and gut health.
Dosing
Typical Protocol
500 mg–6 g oral daily in divided doses; the longevity study used 1,000 mg/kg in mice (human equivalent approximately 3–6 g/day).
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Regulatory
Legal Status in 2026
This compound has completed clinical trials and received formal FDA approval for one or more indications. It can be legally prescribed by licensed physicians, filled at any licensed pharmacy, and may be covered by insurance. Off-label use by physicians is also legal. This is the highest level of regulatory clearance available in the US.
Evidence
Evidence Tier
Evidence from randomized controlled trials (RCTs) or large observational studies in humans. This is the gold standard — effects have been measured in controlled conditions and results are peer-reviewed and reproducible.
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