Tesamorelin
Also sold as Egrifta
Regulatory
Legal Status in 2026
FDA-approved finished drug with an active marketing authorization.
This compound has completed clinical trials and received formal FDA approval for one or more indications. It can be legally prescribed by licensed physicians, filled at any licensed pharmacy, and may be covered by insurance. Off-label use by physicians is also legal. This is the highest level of regulatory clearance available in the US.
About
About Tesamorelin
Tesamorelin is an FDA-approved GHRH analog indicated for HIV-associated lipodystrophy and is used off-label in optimization medicine for visceral fat reduction and cognitive enhancement. Clinical data shows significant reductions in visceral adipose tissue and emerging evidence suggests neuroprotective benefits in older adults. It produces stronger and more sustained GH elevation than sermorelin. Compounded versions are available through licensed pharmacies.
Science
Mechanism of Action
Binds GHRH receptors with high affinity and a stabilized structure that resists degradation, producing robust and sustained GH pulse amplification and downstream IGF-1 elevation.
Dosing
Typical Protocol
1–2 mg subcutaneous injection once daily in the evening.
⚠ Protocol information is for educational purposes only. Dosing must be determined by a licensed physician based on individual health status and goals.
Evidence
Evidence Tier
Evidence from randomized controlled trials (RCTs) or large observational studies in humans. This is the gold standard — effects have been measured in controlled conditions and results are peer-reviewed and reproducible.
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This page evaluates compliance signals, not clinical outcomes. Consult a licensed physician before starting any therapy, medication, or treatment. Vial does not provide medical advice.