VIAL
Compound comparison

ARA-290 vs Sermorelin

ARA-290 and Sermorelin are both peptide compounds evaluated on Vial: ARA-290 is not FDA approved for human use with clinical-trial evidence, and Sermorelin is available as a compounded preparation with clinical-trial evidence.

Vial summary · compiled from public records

At a glance

ARA-290

Category
Peptide
FDA / legal status
Gray Market
Route
0providers on Vial →

Sermorelin

Category
Peptide
FDA / legal status
Compoundable
Route
Subcutaneous
27providers on Vial →

Side by side

FieldARA-290Sermorelin
CategoryPeptidePeptide
Brand names
FDA / legal statusGray MarketCompoundable
Evidence tierClinical TrialsClinical Trials
Administration routeSubcutaneous
Compounding accessNot FDA approved, limited regulated accessAvailable through 503A and 503B compounding pharmacies
Providers on Vial0 listed27 listed
Typical price bandVaries by provider$ to $$$

Verified providers offering each

Ranked by Confidence Rating, Vial’s 0 to 100 score built from federal and state public records. The score evaluates the provider, not the compound.

85+ High Confidence70 to 84 Well Documented50 to 69 Limited ConfidenceUnder 50 Flagged

About each compound

About ARA-290

ARA-290 is a synthetic 11-amino-acid peptide that selectively activates the innate repair receptor (a heterodimer of the EPO receptor and beta common receptor) without erythropoietic effects, providing neuroprotection, anti-inflammatory, and tissue-repair actions. It has completed Phase II trials for neuropathic pain in sarcoidosis and is being studied for small fiber neuropathy, diabetic neuropathy, and inflammatory conditions. It represents a novel approach to harnessing erythropoietin's tissue-protective properties without its blood-thickening risks.

About Sermorelin

A synthetic analog of growth hormone-releasing hormone (GHRH), this 29-amino acid peptide stimulates the pituitary gland to produce and secrete endogenous growth hormone through binding to GHRH receptors. It functions by mimicking the N-terminal bioactive portion of native GHRH, promoting pulsatile GH release while preserving the body's natural feedback mechanisms. Primary applications include diagnostic testing of pituitary function and therapeutic use in growth hormone deficiency.

Descriptions compiled from public FDA records and manufacturer labeling where available. Not medical advice.

This page evaluates compliance signals, not clinical outcomes. Consult a licensed physician before starting any therapy, medication, or treatment. Vial does not provide medical advice.

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