Ipamorelin vs Sermorelin
Ipamorelin and Sermorelin are both peptide compounds evaluated on Vial: Ipamorelin is available as a compounded preparation with clinical-trial evidence, and Sermorelin is available as a compounded preparation with clinical-trial evidence, offered by 20 and 26 verified providers respectively.
Vial summary · compiled from public records
At a glance
Side by side
| Field | Ipamorelin | Sermorelin |
|---|---|---|
| Category | Peptide | Peptide |
| Brand names | — | — |
| FDA / legal status | Compoundable | Compoundable |
| Evidence tier | Clinical Trials | Clinical Trials |
| Administration route | Subcutaneous | Subcutaneous |
| Compounding access | Available through 503A and 503B compounding pharmacies | Available through 503A and 503B compounding pharmacies |
| Providers on Vial | 20 listed | 26 listed |
| Typical price band | $$ to $$$ | $ to $$$ |
Verified providers offering each
Ranked by Confidence Rating, Vial’s 0 to 100 score built from federal and state public records. The score evaluates the provider, not the compound.
About each compound
About Ipamorelin
A synthetic pentapeptide growth hormone secretagogue, ipamorelin selectively stimulates pituitary release of growth hormone by mimicking ghrelin and binding to the growth hormone secretagogue receptor (GHS-R). Unlike earlier secretagogues, it demonstrates high selectivity for GH release with minimal effect on cortisol, prolactin, or appetite-regulating hormones. Research applications have focused on its potential use in growth hormone deficiency, age-related muscle loss, and bone metabolism studies.
About Sermorelin
A synthetic analog of growth hormone-releasing hormone (GHRH), this 29-amino acid peptide stimulates the pituitary gland to produce and secrete endogenous growth hormone through binding to GHRH receptors. It functions by mimicking the N-terminal bioactive portion of native GHRH, promoting pulsatile GH release while preserving the body's natural feedback mechanisms. Primary applications include diagnostic testing of pituitary function and therapeutic use in growth hormone deficiency.
Descriptions compiled from public FDA records and manufacturer labeling where available. Not medical advice.
This page evaluates compliance signals, not clinical outcomes. Consult a licensed physician before starting any therapy, medication, or treatment. Vial does not provide medical advice.
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